BIOCHEMISTRY OF NUTRITION

BIOCHEMISTRY OF NUTRITION

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iten
Code
104208
ACADEMIC YEAR
2020/2021
CREDITS
6 credits during the 1st year of 11158 APPLIED AND EXPERIMENTAL BIOLOGY (LM-6) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
BIO/10
TEACHING LOCATION
GENOVA (APPLIED AND EXPERIMENTAL BIOLOGY)
semester
1° Semester
Teaching materials

OVERVIEW

Nutritional Biochemistry studies the aspects relating to the composition of foods, their nutritional properties and their contribution as structural and functional components in maintaining the physiological homeostasis of the organism.

AIMS AND CONTENT

LEARNING OUTCOMES

The teaching course of Biochemistry of Nutrition aims to provide students the knowledge of the biochemical and nutritional characteristics of micro and macronutrients including several aspects: 1) the functional and modulating value of such nutrients in metabolism, 2) their specific role in the biochemical mechanisms that underlie the main metabolic pathways, 3) their function in the regulation and integration of the different catabolic and anabolic systems. Students will become able to analyze the metabolic fate of the foods in order to identify systems capable of regulating the bioavailability and absorption of the main nutrients recognizing the possible metabolic interactions between nutrients. At the end of the course the students

AIMS AND LEARNING OUTCOMES

The aim of this teaching is to give a basic knowledge about rhe role of micro and macronutrients. In particular, it will be investigated the role of vitamins, carbohydrates, lipids and proteins as a function of their bioavailability in conditions of both nutritional and assimilation deficiencies. In this context, the student will have to acquire the ability to analyze the metabolic fate of the main foods and to identify the strategies necessary to increase their bioavailability and assimilation. The student will also be able to identify the metabolic interactions among the nutrients, highlighting the nutritional deficiencies deriving from unbalanced diets.

PREREQUISITES

Knowledge of general biochemistry and energy metabolism

Teaching methods

The lessons will be carried out if possible in presence, guaranteeing however the fruition of the lessons even remotely, through video recording, synchronous or asynchronous. All face-to-face activities will be carried out in compliance with the classroom capacity limits and the distance provided for by current legislation following the COVID19 emergency.

Please refer to the specific AulaWeb application  for any updates due to changes in the health and epidemiological situation.

SYLLABUS/CONTENT

Sources and bioavailability of nutrients. Energy and plastic nutrients. Macronutrients and micronutrients. Vitamins. Inorganic nutrients.

Molecular mechanism of the activation and hydrolytic action of digestive enzymes for the use of nutrients.
Carbohydrates. Digestion and assimilation. Glycemic index of foods. Chemical nature and properties of simple sugars and polysaccharides. Glycogen and starch. Organization of starch granules. Soluble and insoluble dietary fibers. Sources of simple sugars, starch and vegetable fiber.

Lipids. Digestion and assimilation. Chemical nature and properties of fatty acids, triglycerides, phospholipids, cholesterol and derivatives. Essential fatty acids.
Proteins. Digestion and assimilation. Chemical nature and properties of amino acids, polypeptides and proteins. Essential amino acids and nutritional properties of proteins. Meat and other animal sources of protein. Gluten and other vegetable proteins.

Non-protein nitrogen compounds: glutathione, carnitine. etc ...
Metabolism and bioenergetics. Aspects of energy metabolism and its regulation. Hormonal integration and regulation of metabolism. Metabolic specialization of organs and tissues. Liver metabolism and the main extrahepatic tissues. Energy reserves. The biochemistry of glycemic homeostasis. Metabolic pathways of carbohydrates, lipids, and nitrogen compounds. Metabolic regulation in the diet-fasting cycle.

Ethanol metabolism. Antioxidants and oxidative stress. Enzymatic mechanisms of detoxification: cytochromes P450 (CYP) and flavin-dependent monooxygenase (FMO).

xenobiotics

RECOMMENDED READING/BIBLIOGRAPHY

-Biochimica della nutrizione Ugo Leuzzi, Ersilia Bellocco, Davide Barreca -Zanichelli

-Le basi molecolari della nutrizione Giuseppe Arienti -Piccin quarta edizione

TEACHERS AND EXAM BOARD

Ricevimento:  Students can meet the teachers by booking individual appointments. The teachers  can be contacted  either by e-mail or telephone. e mail: monica.averna@unige.it  phone: 010 3538423 

Ricevimento: Students can meet the teacher by booking individual appointments. The teacher can be contacted either by e-mail or telephone. e-mail: roberta.detullio@unige.it  phone: 010 3538160 

Exam Board

MONICA AVERNA (President)

ROBERTA DE TULLIO (President Substitute)

LESSONS

Teaching methods

The lessons will be carried out if possible in presence, guaranteeing however the fruition of the lessons even remotely, through video recording, synchronous or asynchronous. All face-to-face activities will be carried out in compliance with the classroom capacity limits and the distance provided for by current legislation following the COVID19 emergency.

Please refer to the specific AulaWeb application  for any updates due to changes in the health and epidemiological situation.

LESSONS START

Consult detailed timetable at the following link: https://easyacademy.unige.it/portalestudenti/

ORARI

L'orario di tutti gli insegnamenti è consultabile su EasyAcademy.

Vedi anche:

BIOCHEMISTRY OF NUTRITION

EXAMS

Exam description

Oral exam. Please refer to the specific AulaWeb application  for any updates due to changes in the health and epidemiological situation.

Assessment methods

Oral examination with assessment of knowledge and ability to link between the various topics in the program. To establish the degree of competence acquired by the students, with respect to the program of this teaching, the commission will positively evaluate the ability to analyze and integrate different aspects of the proposed question and the use of an appropriate vocabulary.

Exam schedule

Date Time Location Type Notes
08/04/2021 15:00 GENOVA Orale
21/06/2021 15:00 GENOVA Orale
12/07/2021 15:00 GENOVA Orale
10/09/2021 15:00 GENOVA Orale