BIOCHEMISTRY
OVERVIEW
Biochemistry, together with molecular biology and human genetics, is necessary to understand the molecular events underlying human physiology and pathology. This Course will teach the basic mechanisms of chemical and metabolic modifications in order to understand the molecular basis of diseases.
AIMS AND CONTENT
AIMS AND LEARNING OUTCOMES
At the end of this course, the student must have acquired an understanding of the biochemical reactions of the major anabolic and catabolic pathways, and of their relevance to understand the molecular basis of disease.
Teaching methods
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Lectures will cover the entire program of the course. Three different Professors (Salamino, Tonetti e Zocchi) will alternate during the course, covering different parts of the program, as indicated in sylabus/ content. At the end of the lessons, at least 4 hours will be devoted to question-time by the students with the three Professors together. |
SYLLABUS/CONTENT
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Proteins: composition and structure (Teacher Prof. Santina Bruzzone) Proteins:structure-function relationships in protein families (Teacher Prof. Santina Bruzzone) Enzymes: classification kinetics and control (Teacher Prof. Santina Bruzzone) Bioenergetics and oxidative metabolism (Teacher Prof. Santina Bruzzone) Carbohydrate metabolism: major metabolism and their control (Teacher Prof. Michela Tonetti) Carbohydrate metabolism: special pathways (Teacher Prof. Michela Tonetti) Lipid metabolism: transport, utilization and storage of energy in lipid form (Teacher Prof. Santina Bruzzone) Lipid metabolism: pathways of metabolism of special lipids (Teacher Prof. Santina Bruzzone) Aminoacid metabolism (Teacher Prof. Elena Zocchi) Purine and pyrimidine nucleotide metabolism: metabolic interrelationships (Teacher Prof. Elena Zocchi) Biochemistry of hormones: polypeptide hormones(Teacher Prof. Elena Zocchi) Biochemistry of hormones: steroid hormones (Teacher Prof. Elena Zocchi) Biochemistry of liver, muscle and adipose tissue (Teacher Prof. Elena Zocchi) Iron and heme metabolism (Teacher Prof. Santina Bruzzone) Principle of nutrition: water soluble vitamins and lipid soluble vitamin(Teacher Prof. Michela Tonetti) |
RECOMMENDED READING/BIBLIOGRAPHY
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Materials published in Aula Web Texbook: Nelson and Cox: Lehninger Principles of Biochemistry w.h. freeman ed. Devlin: Textbook of biochemistry with clinical correlations Wiley-Liss ed |
TEACHERS AND EXAM BOARD
Ricevimento: The teacher receives by appointment at Biochemistry - DIMES, Viale Benedetto XV No. 1, first floor, Genoa. The talks may take place, by appointment, also via Skype For appointments please send an email to: tonetti@unige.it.
Ricevimento: By appointment by email: santina.bruzzone@unige.it Office: DIMES, Section of Biochemistry, Viale Benedetto XV, 1 (Genova) Phone: 0103538161
Exam Board
SANTINA BRUZZONE (President)
GIANLUCA DAMONTE (President)
MICHELA TONETTI
ELENA ZOCCHI
LESSONS
Teaching methods
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Lectures will cover the entire program of the course. Three different Professors (Salamino, Tonetti e Zocchi) will alternate during the course, covering different parts of the program, as indicated in sylabus/ content. At the end of the lessons, at least 4 hours will be devoted to question-time by the students with the three Professors together. |
LESSONS START
6 march 2017
EXAMS
Exam description
Oral exam. Students should pass the Biochemistry 1 test before enlisting for the Biochemistry 2 oral exam. The final score will include both subjects.
Assessment methods
The assessment takes place only through the final exam which aims to ensure the effective acquisition by the student of the expected learning outcomes.
Exam evaluation will take into account knowledge, presentation/speaking skills, as well as the ability in connecting the different arguments.