MOLECULAR, CELLULAR AND TISSUE ENGINEERING

MOLECULAR, CELLULAR AND TISSUE ENGINEERING

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Code
80724
ACADEMIC YEAR
2019/2020
CREDITS
6 credits during the 1st year of 8725 Bioengineering (LM-21) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
ING-IND/34
LANGUAGE
Italian (English on demand)
TEACHING LOCATION
GENOVA (Bioengineering)
semester
2° Semester
Teaching materials

AIMS AND CONTENT

LEARNING OUTCOMES

The teaching aims to provide knowledge both on fundamental and technological aspects of tissue engineering, with particular reference to:

  • cell biology
  • biomaterials
  • biocompatibility
  • biomolecular engineering 
  • regenerative medicine

AIMS AND LEARNING OUTCOMES

The teaching is intended to provide theoretical and practical tools for understanding and solving problems in the field of tissue engineering. The main aim is underline the importance of understanding biological phenomena at the molecular, cellular and tissue level in order to develop therapeutic strategies that can overcome the limits of conventional therapies. The applicative examples, that will be proposed, will thus have the purpose of stimulating and developing the student's abilities in applying theoretical knowledge to the field of tissue engineering.

Teaching methods

Combination of traditional lectures (40 hours) and laboratory (8 hours). 

SYLLABUS/CONTENT

•    Chemical Bioengineering: biomolecules, structure-function relationship, biomolecules in bioengineering applications.
•    Fundamentals of biotechnology: recombinant DNA and genetic techniques.
•    Fundamentals of cytology: structure and function of the eukaryotic cell, the extracellular matrix, cell adhesion mechanisms.
•    Maintenance and expansion of in vitro cell cultures. Primary cells, immortalized cells and stem cells.
•    Definition of biological tissue and of its organization.
•    Biomaterials for regenerative medicine: hydrogels.
•    Techniques for the evaluation of biocompatibility: in vitro, in vivo and clinical trials. Methodologies for the modification of the surface properties of biomaterials. Bioreactors.
•    Micro and nano systems for the controlled release of drugs and biomolecules.

RECOMMENDED READING/BIBLIOGRAPHY

Teaching material available on Aulaweb.

TEACHERS AND EXAM BOARD

Ricevimento: Appointments by e-mail.

Exam Board

LAURA PASTORINO (President)

CARMELINA RUGGIERO

MAURO GIACOMINI

DONATELLA DI LISA

ELENA DELLACASA

FABRIZIO BARBERIS

LESSONS

Teaching methods

Combination of traditional lectures (40 hours) and laboratory (8 hours). 

EXAMS

Exam description

Oral exam

Assessment methods

At the end of the teaching the student must demonstrate to:

  • Have understood the fundamental aspects of molecular, cellular and tissue engineering.
  • Being able to discuss to correlate the diffrent  teaching topics.
  • Discuss the presented technologies starting  from their physiological bases.