ANALYSIS OF DRUGS II

ANALYSIS OF DRUGS II

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Code
80322
ACADEMIC YEAR
2019/2020
CREDITS
8 credits during the 3nd year of 8452 Pharmacy (LM-13) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
CHIM/08
LANGUAGE
Italian
TEACHING LOCATION
GENOVA (Pharmacy)
semester
1° Semester
Prerequisites
Teaching materials

OVERVIEW

The course is focused on the methods for the qualitative analysis of pharmaceutically active (in)organic compounds. The different techniques will be presented by theory class as well as practice sessions in the laboratory.

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

The aim of the course is to provide the theoretical knowledge and the technical skills on the most relevant methods used for the qualitative analysis of a pharmaceutically relevant compound. At the end of the course, the student will be familiar with the different tests used for the chemical identification of the compounds and will be able to critically analyze the experimental results.

PREREQUISITES

Organic and inorganic chemistry

Teaching methods

Lessons and laboratory exercises.

SYLLABUS/CONTENT

Qualitative analysis of inorganic salts: systematic search of anions (phosphates, thiosulphates, iodides, bromides, chlorides, sulphates, nitrates) and cations (silver, barium, bismuth, copper, alluminium, iron, manganese, zinc, calcium, magnesium).

Qualitative analysis of organic compounds: preliminary assays and test for specific functional groups (alcohols, polyalcohols, carbohydrates, phenols, carboxylic acids, esters, amines, amides, aminoacids, sulfonamides, pyridine and purine derivatives).

Spectroscopic methods: UV/VIS, IR, NMR, mass spectrometry.

RECOMMENDED READING/BIBLIOGRAPHY

F. Savelli, O. Bruno, “Analisi Chimico Farmaceutica”, Ed. Piccin

A. Carta, M. G. Mamolo, F. Novelli, S. Piras, “Analisi Farmaceutica Qualitativa”, Ed. EdiSES

TEACHERS AND EXAM BOARD

Ricevimento: By appointment

Exam Board

ANDREA SPALLAROSSA (President)

CHIARA BRULLO (President)

BRUNO TASSO

SILVIA SCHENONE

LESSONS

Teaching methods

Lessons and laboratory exercises.

EXAMS

Exam description

Oral examination (about 30 minutes). The topics of the oral exam will include the reaction mechanisms underlying the different chemical assays and the analysis of UV, IR and NMR spectra of a organic compound.

Assessment methods

The students have to demonstrate the  knowledge of the different topics presented during the course.