EXPERIMENTAL PATHOLOGY

EXPERIMENTAL PATHOLOGY

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iten
Code
67909
ACADEMIC YEAR
2019/2020
CREDITS
1 credits during the 2nd year of 9281 PHYSIOTHERAPY (L/SNT2) GE SAN MARTINO
SCIENTIFIC DISCIPLINARY SECTOR
MED/04
LANGUAGE
Italian
TEACHING LOCATION
GE SAN MARTINO (PHYSIOTHERAPY)
semester
1° Semester
modules
This unit is a module of:
Teaching materials

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

Pathology is the study of disease. It is the bridge between science and medicine.The aim is to teach the origin and the mechanisms underlying the infections, the inflammatory, metabolic, degenerative and neoplastic processes responsible for human pathology. Students will learn: the concept of disease status and the main causes that  lead to cellular and tissue injury; the reaction of the organism in response to cellular and tissue damage; the cellular adaptation processes and inflammation, with the consequent regeneration / healing processes. They will learn the mechanisms underlying tumor development, and the characteristics of neoplastic cells. The stages of the development and progression of tumor and the differences between benign and malignant tumors

Teaching methods

Teaching is divided into 10 hours of classroom lectures on all the topics of the syllabus. The topics are explained by the teacher through PowerPoint presentations. The teacher always recommends the use of a textbook to expand the overall view of the subject.  The language is Italian.

 

SYLLABUS/CONTENT

1) Introduction

Definition of the study field of Pathology. Concept meaning  of homeostasis.

 

2) Etiology

Notion of cause and its characteristics. Classification of causes: intrinsic and extrinsic. Intrinsic causes of disease - Autosomal recessive and dominant diseases.

 Extrinsic causes of illness –

Physical Radiation Definition; classification (corpusculate and electromagnetic). Ionizing and exciting radiation. Ionizing radiation: direct and indirect effects; effects at molecular, cellular, tissue and organ level. Exciting radiation: direct and indirect effects. Temperature: Effects of high and low temperatures at local and systemic level.

Traumas- Main concepts on: traumas of superficial tissues. Trauma of internal organs. Osteoarticular traumas. –

Chemical causes. Mechanisms of chemical substances's pathogenic action . Ph alteration. Solvent action. Denaturing action. Toxic action: definition and concepts of concentration at the active site, dose, distribution volume, time, route of administration. Poison definition. Defense mechanisms against poisons: congenital and acquired defenses.

 

3) Cellular pathology

Concepts of cell adaptation, cell injury; regressive and progressive processes. Atrophies. Hypertrophies and hyperplasia. Cell death: necrosis and apoptosis.

 

4) Inflammation

Acute and chronic inflammation. Acute inflammation: Concept of chemical mediator. Vasoconstriction and vasodilation. Alteration of vascular permeability, hydrostatic and colloid-osmotic pressure. Formation of inflammatory edema. Chemotaxis, migration, margination and diapedesis of leukocytes. Phagocytosis. Systemic inflammation: leukocytosis, fever, acute phase proteins. Septic shock.

Classification of acute inflammation.

Chronic inflammation: cellular characteristics of chronic inflammation and its pathogenesis.  Chronic interstitial and granulomatous inflammations.

5) Healing

Regeneration and repair concepts. Wound healing: first and second intention. Complications.

6) General Oncology

Definition of neoplasia. Characteristics of benign and malignant tumors. Epidemiology of tumors. Molecular bases of cancer: oncogenes, tumor onco-suppressors, genes that regulate apoptosis. Carcinogenesis.

 

RECOMMENDED READING/BIBLIOGRAPHY

GM. PONTIERI-  "Patologia generale e Fisiopatologia generale. Per i corsi di laurea in professioni sanitarie". Ed. Piccin

JAM. MAIER- " Elementi di Patologia generale e Fisiopatologia". Ed. Mc Graw Hill Education

 

TEACHERS AND EXAM BOARD

Ricevimento: By e-mail : chiara.vitale@unige.it By phone : 010-5558219

Ricevimento: By appointment Email: Cristina.Bottino@unige.it

Exam Board

LUIGI ROBBIANO (President)

BARBARA MARENGO (President)

ALESSANDRO SARTESCHI

CHIARA VITALE

ROBERTO FIOCCA

LUCA MASTRACCI

TULLIO FLORIO

CRISTINA BOTTINO

LESSONS

Teaching methods

Teaching is divided into 10 hours of classroom lectures on all the topics of the syllabus. The topics are explained by the teacher through PowerPoint presentations. The teacher always recommends the use of a textbook to expand the overall view of the subject.  The language is Italian.

 

LESSONS START

Classes are in the first semester and start at the beginning of October  . The precise schedule is agreed with the coordinator responsible for the course and communicated on the website. 

EXAMS

Exam description

The exam is an oral one, that consists in an interview with the teacher.

Assessment methods

Verification of learning is carried out through the oral exam, aimed at verifying the real acquisition by the student of the expected learning outcomes. Several items will further contribute to the student evaluation:

-accuracy, clarity, synthesis and fluency;

- competence in the subject;

- speaking ability and correct use of terminology

Exam schedule

Date Time Location Type Notes
17/06/2020 09:00 GENOVA Orale SEDI: Aula Teledidattica Polo Biomedico per esame di Anatomia patologica 15 Gennaio 2020 e 08 Luglio 2020: AULA 8 POLO BIOMEDICO TUTTE LE ALTRE DATE: AULA 7 POLO BIOMEDICO per il resto dell'esame
08/07/2020 09:00 GENOVA Orale SEDI: Aula Teledidattica Polo Biomedico per esame di Anatomia patologica 15 Gennaio 2020 e 08 Luglio 2020: AULA 8 POLO BIOMEDICO TUTTE LE ALTRE DATE: AULA 7 POLO BIOMEDICO per il resto dell'esame
02/09/2020 09:00 GENOVA Orale SEDI: Aula Teledidattica Polo Biomedico per esame di Anatomia patologica 15 Gennaio 2020 e 08 Luglio 2020: AULA 8 POLO BIOMEDICO TUTTE LE ALTRE DATE: AULA 7 POLO BIOMEDICO per il resto dell'esame
16/09/2020 09:00 GENOVA Orale SEDI: Aula Teledidattica Polo Biomedico per esame di Anatomia patologica 15 Gennaio 2020 e 08 Luglio 2020: AULA 8 POLO BIOMEDICO TUTTE LE ALTRE DATE: AULA 7 POLO BIOMEDICO per il resto dell'esame