BIOORGANIC CHEMISTRY

BIOORGANIC CHEMISTRY

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iten
Code
34001
ACADEMIC YEAR
2019/2020
CREDITS
4 credits during the 3nd year of 8757 Chemistry and Chemical Technologies (L-27) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
CHIM/06
LANGUAGE
Italian
TEACHING LOCATION
GENOVA (Chemistry and Chemical Technologies)
semester
2° Semester
Prerequisites
Teaching materials

AIMS AND CONTENT

LEARNING OUTCOMES

To give a general idea of various aspects where organic chemistry is connected with biology. In  particular: structure functioning of proteins (enzymes, receptors, channels) and oligosaccharides, and their interaction with potential drugs.

Teaching methods

Traditional lessons in the classroom (32 hours). The attendance is not compulsory but, for statistical means, it wil be anyway monitored.

SYLLABUS/CONTENT

Protein: secondary, tertiary and quaternary structure Enzymes: kynetics, catalysis mechanism, examples, classification . Principle of drug discovery. Enzyme inhibitors, receptors, ion channels. Glycochemistry. Applications in the fields of antiviral, antitumor drugs, antibiotics, antiinflammatory drugs, anti-asthma drugs, drugs for cardiovascular diseases and so on.

RECOMMENDED READING/BIBLIOGRAPHY

  • Silverman, R.B., "The Organic Chemistry of Drug Design and Drug Action", Academic Press
  • Corey, E.J., Czakó, B. Kürti, L., "Molecules and Medicines", Wiley

TEACHERS AND EXAM BOARD

Ricevimento: The teacher is always present in the Department between 8.00 and 13.00 and 15.00 and 18.30 (except in august). The students can come to speak with him in any moment, unless he is engaged in other isntitutional activities. However, it is highly advised to arrange an appointment by E-mail, in order to be sure to find him free.

Exam Board

LUCA BANFI (President)

RENATA RIVA

LISA MONI

CHIARA LAMBRUSCHINI

ANDREA BASSO

LESSONS

Teaching methods

Traditional lessons in the classroom (32 hours). The attendance is not compulsory but, for statistical means, it wil be anyway monitored.

LESSONS START

2 march 2020 (timetable on http://www.chimica.unige.it/didattica/orari_CTC  or https://corsi.unige.it/8757)

EXAMS

Exam description

The exam will be oral. Only the subjects treated during the lessons (as reported in the slides deposited in aulaweb) will be object of the exam. Students must register to the exam at least 48 hours in advance on https://servizionline.unige.it/studenti/esami/prenotazione

Assessment methods

The oral exam is always carried out by two teachers with at least 5 years of experience and will last at least 30 minutes. In this way, the commission is definitely able to verify with high accuracy if the student has reached or not the learning outcomes.

During the oral exam the student must demonstrate to have reached the learning outcomes, both orally and (most importantly) writing formulas, chemical equations, mechanisms.

When the commission will judge that the learning oucomes have not been reached, the students will be invited to repeat the exam in one of the subsequent dates.