BIOCHEMISTRY

BIOCHEMISTRY

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iten
Code
75096
ACADEMIC YEAR
2018/2019
CREDITS
1 credits during the 1st year of 9293 BIOMEDICAL LABORATORY TECHNIQUES (L/SNT3) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
BIO/10
LANGUAGE
Italian
TEACHING LOCATION
GENOVA (BIOMEDICAL LABORATORY TECHNIQUES)
semester
2° Semester
modules
This unit is a module of:
Teaching materials

OVERVIEW

The course consist of two modules: Propedeutical Biochemistry and Biochemistry, and is divided into two parts: a part of lessons in presence and one part, as support of the first, consisting of online classes.

AIMS AND CONTENT

LEARNING OUTCOMES

The first part of the course aims to provide the basis of general and organic chemistry to address Biochemistry,  the second part of the course. The aim of this second part is both the acquisition of knowledge about the structure and function of proteins and enzymes proteins as the main pathways of carbohydrate, fat, and protein catabolism.

AIMS AND LEARNING OUTCOMES

The first part of the course aims to provide the basis of general and organic chemistry to address Biochemistry,  the second part of the course. The aim of this second part is both the acquisition of knowledge about the structure and function of proteins and enzymes proteins as the main pathways of carbohydrate, fat, and protein catabolism.

Teaching methods

Lectures in presence,supported / supplemented by recorded lectures  that the students can access online through the platform AulaWeb

SYLLABUS/CONTENT

PROPEDEUTICAL BIOCHEMISTRY solutions. Properties and  units of measure: molarity, normality,% w / w% w / v. osmotic pressure. The chemical reactions. chemical balance. chemical kinetics. Reaction speed. Catalysis and enzymatic catalysis, Km. Thermodynamics. Concepts of enthalpy and entropy. Spontaneity of reactions, free energy. Ionization of water. pH. Acidity and alkalinity. Strong and weak acids and bases,  hydrolysis, buffers. The chemistry of carbon, the carbon valence. The functional groups. Alcohols and thiols. Redox reactions. Oxidation of alcohols and thiols. Aldehydes and ketones. Hemiacetals. Amines. Carboxylic acid. Amides, esters and anhydrides. Fatty acids. Triglycerides. Phospholipids. Biomolecules and their functional groups. Carbohydrates: Monosaccharides: glucose, fructose, ribose and deoxyribose, disaccharides: sucrose, and polysaccharides, cellulose, glycogen. Amino acids. Peptides and proteins. The peptide bond. protein structure.

Biochemistry Myoglobin.  Hemoglobin. Enzymes: structure and function. Catabolism and anabolism: general concepts of the intermediate metabolism. Glycolysis, gluconeogenesis and glucose:  regulation. Lactate cycle. Krebs cycle. Strategies for ATP synthesis. Synthesis and degradation of glycogen. Oxidation of fatty acids. Chetonic bodies. Amino acids catabolism: urea cycle.

RECOMMENDED READING/BIBLIOGRAPHY

Catani, Savini, Guerrieri, Avigliano “Appunti di Biochimica per le lauree triennali” Editore: Piccin
Stefani, Taddei “Chimica biochimica e biologia applicata” Editore: Zanichelli

TEACHERS AND EXAM BOARD

Ricevimento: Prof. Umberto Benatti, Viale Benedetto XV, 1 - 16132 Genova Tel: 010-3538151  e-mail: benatti@unige.it Dr. Mario Passalacqua, Via LB Alberti 2 , 16132 Genova Tel 010-3538835  e-mail: Mario.Passalacqua@unige.it

Exam Board

PIETRO BALDELLI

MARIO PASSALACQUA

UMBERTO BENATTI

LESSONS

Teaching methods

Lectures in presence,supported / supplemented by recorded lectures  that the students can access online through the platform AulaWeb

LESSONS START

II SEMESTER – STARTING FROM MARCH 2017

EXAMS

Exam description

Oral examination

Assessment methods

For the units with video lessons,  self-assessment tests, which are designed to stimulate students in learning, are provided.  Self-assessment tests are useful also to verify the correct understanding, facilitating the preparation of the final exam, done in the presence.