GENERAL MEDICINAL CHEMISTRY AND MEDICINAL CHEMISTRY I

GENERAL MEDICINAL CHEMISTRY AND MEDICINAL CHEMISTRY I

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Code
80319
ACADEMIC YEAR
2018/2019
CREDITS
12 credits during the 3nd year of 8452 Pharmacy (LM-13) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
CHIM/08
LANGUAGE
Italian
TEACHING LOCATION
GENOVA (Pharmacy)
Prerequisites
Teaching materials

OVERVIEW

The drug-discovery process as well as the structure-activity relationships of the different classes of chemotherapeutic agents and hormones (peptide and steroidal) are presented in the course

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

The course aims at presenting the relevant approaches currently used in the drug discovery process and the structure-activity relationships developed for chemotherapeutic agents (i.e. antibacterial, antiviral and antitumor agents) and for steroidal/peptide hormones. This knowledge is part of the cultural background characterizing a pharmacist as an healthcare professional.

Teaching methods

Lectures

SYLLABUS/CONTENT

The first part of the course is focussed on the drug discovery process with particular emphasis on computer aided drug design and combinatorial chemistry.

The second part deals with the synthetic strategies, the structure-activity relationships and the pharmacokinetic/pharmacodynamic properties of different classes of chemotherapeutic drugs (e.g. antibacterial, antiprotozoal, antimycotic, antiviral and antitumor agents) and steroidal/peptide hormones.

RECOMMENDED READING/BIBLIOGRAPHY

Foye's. Principi di chimica farmaceutica. Piccin

Wilson & Gisvold. Chimica Farmaceutica. Casa Editrice Ambrosiana

Gasco, Gualtieri, Melchiorre. Chimica faramceutica. Casa Editrice Ambrosiana

TEACHERS AND EXAM BOARD

Ricevimento: By appointment

Exam Board

ANDREA SPALLAROSSA (President)

BRUNO TASSO

SILVIA SCHENONE

FRANCESCA MUSUMECI

CHIARA BRULLO

LESSONS

Teaching methods

Lectures

EXAMS

Exam description

Oral examination

Assessment methods

The exam is directed to the evaluation of the learning, the communicative and problem-solving skills of the student