GENERAL PHYSIOLOGY (PCT)MD)

GENERAL PHYSIOLOGY (PCT)MD)

_
iten
Code
60829
ACADEMIC YEAR
2018/2019
CREDITS
8 credits during the 2nd year of 8451 Pharmaceutical chemistry and technology (LM-13) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
BIO/09
LANGUAGE
Italian
TEACHING LOCATION
GENOVA (Pharmaceutical chemistry and technology)
semester
2° Semester
Prerequisites
Teaching materials

OVERVIEW

The course intends to provide basic knowledge about the functioning of cells and the human organism. These notions are propaedeutic to the understanding of the interactions between the organism and drugs or other physical and chemical agents endowed with biological activity, i.e. able to modify the functional status of the human organism.

AIMS AND CONTENT

LEARNING OUTCOMES

Providing basic knowledge about the mechanisms governing cell functions: cell-cell communication, nervous impulse transmission, synaptic transmission, sensory receptors, and muscle contraction. Illustrating the functions of the body organs and systems: cardiovascular function, immune system, respiration, excretion-osmoregulation, nutrition-bioenergetics, endocrine system, and reproduction.

AIMS AND LEARNING OUTCOMES

The course intends to make students able to apply the acquired knowledge to the analysis of questions, the solution of problems, and to illustrate the topics of the syllabus.

Teaching methods

Class lessons with exercise and teaching materials on the University’s AulaWeb platform.

SYLLABUS/CONTENT

General principles

• Definition of Physiology.

• Features of living beings.

• Chemical composition of living matter.

• Homeostasis and exercise physiology.

 

Cells

• Cell membrane. Diffusion, osmosis. Membrane transport.

• Cell communication. Signal molecules, cell receptors. Signal transduction pathways.

• Diffusion and equilibrium potentials. Donnan equilibrium, pump-and-leak model, RVD, RVI.

• Membrane currents and EF measurements. Action potential.

• Intracellular calcium signaling and homeostasis.

• Synapses.

 

Sistems

• Central nervous system. Brain, mesencephalon, cerebellum. Effector systems.

• Sensory system, skin receptors. Eye, photoreceptors and neural retina. Ear and vestibular system, taste, smell.

• Endocrine system, hypothalamic–pituitary axis, pineal gland, thyroid. Parathyroid gland, calcium balance, adrenal glands. Glicogen metabolism. Gonads.

• Muscular system, striated muscle fiber, muscle contraction. Types of muscle fibers.

• Body’s liquids, blood composition. Hemostasis, lymphatic system. Immune system.

• Cardiovascular system, electric activity, contraction. Cardiac cycle. Vessels, flux, pressure, capillaries. Veins, pressure regulation.

• Respiratory system and dynamics. Lung volumes, gas exchange, oxygen transport. Control of respiration, CO2 transport, ventilation/perfusion ratio.

• Kidney, filtration and reabsorption. Urine concentration, salt water balance. Acid-base homeostasis, alkalosis, acidosis.

• Digestive system, salivary glands, stomach. Liver, pancreas. Gastrointestinal motility and absorption.

• Male reproductive system. Female reproductive system, menstrual cycle. Fertilization, pregnancy.

• Energy balance.

RECOMMENDED READING/BIBLIOGRAPHY

Section on cells: V. Taglietti, C. Casella. Fisiologia e Biofisica delle Cellule, EdiSES. Napoli .

Section on systems (one of the following):

  • D.U. Silverthorn. Fisiologia. Pearson .
  • W.J. Germann, C. L. Stanfield. Fisiologia. EdiSES. Napoli.
  • L. Sherwood. Fisiologia Umana. Zanichelli.

Teaching materials on the University’s AulaWeb platform.

TEACHERS AND EXAM BOARD

Ricevimento: Appointment made by mail: burlando@difar.unige.it

Exam Board

BRUNO PIETRO BURLANDO (President)

SILVIO PALMERO

ILARIA DEMORI

LESSONS

Teaching methods

Class lessons with exercise and teaching materials on the University’s AulaWeb platform.

EXAMS

Exam description

Combined written and oral exam.

Assessment methods

Combined written and oral exam assessing the student's ability of using the acquired knowledge to analyze and respond to questions, solve problems, and illustrate the topics of the syllabus.

Exam schedule

Date Time Location Type Notes
06/09/2019 09:00 GENOVA Scritto + Orale
06/09/2019 09:00 GENOVA Scritto + Orale Aula informatica Polo Alberti (Piano III)
17/09/2019 14:00 GENOVA Scritto + Orale
17/09/2019 14:00 GENOVA Scritto + Orale Aula informatica Polo Alberti (Piano III)
21/01/2020 09:00 GENOVA Scritto + Orale
21/01/2020 09:00 GENOVA Scritto + Orale Aula informatica Polo Alberti (Piano III)
04/02/2020 09:00 GENOVA Scritto + Orale Aula informatica Polo Alberti (Piano III)