CELL BIOLOGY II AND LABORATORY COURSE

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Code
95302
ACADEMIC YEAR
2017/2018
CREDITS
6 credits during the 1st year of 10598 MEDICAL-PHARMACEUTICAL BIOTECHNOLOGY (LM-9) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR
BIO/13
LANGUAGE
English
TEACHING LOCATION
GENOVA (MEDICAL-PHARMACEUTICAL BIOTECHNOLOGY)
semester
1° Semester
Prerequisites
Prerequisites (for future units)
This unit is a prerequisite for:
  • MEDICAL-PHARMACEUTICAL BIOTECHNOLOGY 10598 (coorte 2017/2018)
  • MOLECULAR BIOLOGY 2 AND LABORATORY 95300
Teaching materials

AIMS AND CONTENT

LEARNING OUTCOMES

Comprehensive analysis of stem cell biology, with specific focus on their differentiation and therapeutic potential (including somatic nuclear transfer and cloning).

TEACHING METHODS

Frontal lessons and laboratory.

SYLLABUS/CONTENT

Stem cells: stemness characterisation and historical background.

Embryonic – Fetal – Adult Stem Cells. Stem versus Differentiation Potential.

The Stem Cell Niche. Stem Cell Pluripotency and Plasticity. Stem Cell Markers and “Stem Genes”.

Adult Stem Cells: Haematopoietic-, Epithelial-, Neural- and Mesenchymal Stem Cells.

Somatic Nuclear Transfer in amphibians and mammals. Cloning.

Fetal and Perinatal Stem Cells

EMT in Cell Biology: Epithelial - Mesenchymal Transition

Tissue-Specific Adult Progenitors within the Heart.

Epicardial Progenitor Cells (EPDC): Proof-of-Principle of EMT in Cardiac Development and Regeneration.

Tissue-Specific Adult Progenitors within the Skeletal Muscle.

Stem Cells, DNA damage & Ageing.

Stem Cells & miRNA

Inter-Cellular Communication 2.0: Extracellular Microvesicles

De-Differentiation, Trans-Differentiation and Reprogramming.

 

Journal Club: Oral presentation from groups of students on specific articles from the topic discussed during class.

 

Hands On Practice on Cell Culture Laboratory

TEACHERS AND EXAM BOARD

Office hours: By appointment by email: sveva.bollini@unige.it  

Office hours: By appointment by email: ranieri.cancedda@unige.it

Exam Board

SVEVA BOLLINI (President)

CHIARA GENTILI (President)

RANIERI CANCEDDA

LESSONS

TEACHING METHODS

Frontal lessons and laboratory.

LESSONS START

October 1, 2017

EXAMS

EXAM DESCRIPTION

Written

ASSESSMENT METHODS

Written test

Exam schedule

Date Time Location Type Notes
16/01/2018 14:00 GENOVA Orale c/o Aula – Torre A piano 3 CBA
13/02/2018 14:00 GENOVA Orale c/o Aula – Torre A piano 3 CBA
18/06/2018 14:00 GENOVA Orale c/o Aula – Torre A piano 3 CBA
16/07/2018 14:00 GENOVA Orale c/o Aula – Torre A piano 3 CBA
17/09/2018 14:00 GENOVA Orale c/o Aula – Torre A piano 3 CBA